WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_CAGCTG_V$AP4_Q5       ID:DB_ID:2403
C=1502; O=16; E=1.60; R=9.99; rawP=1.60e-12; adjP=4.02e-10
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
2  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
3  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
4  ENSG00000125355 NA FAM70A family with sequence similarity 70, member A 55026 ENSG00000125355
5  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
6  ENSG00000175161 NA CADM2 cell adhesion molecule 2 253559 ENSG00000175161
7  ENSG00000197757 NA HOXC6 homeobox C6 3223 ENSG00000197757
8  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449
9  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
10  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
11  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
12  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
13  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
14  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
15  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
16  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910


Database:Transcription Target       Name:hsa_CTTTGT_V$LEF1_Q2       ID:DB_ID:2428
C=1939; O=17; E=2.07; R=8.22; rawP=5.90e-12; adjP=7.40e-10
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000125851 NA PCSK2 proprotein convertase subtilisin/kexin type 2 5126 ENSG00000125851
2  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
3  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
4  ENSG00000125355 NA FAM70A family with sequence similarity 70, member A 55026 ENSG00000125355
5  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
6  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069
7  ENSG00000197757 NA HOXC6 homeobox C6 3223 ENSG00000197757
8  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449
9  ENSG00000144847 NA IGSF11 immunoglobulin superfamily, member 11 152404 ENSG00000144847
10  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
11  ENSG00000187123 NA LYPD6 LY6/PLAUR domain containing 6 130574 ENSG00000187123
12  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
13  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203
14  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
15  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
16  ENSG00000162873 NA KLHDC8A kelch domain containing 8A 55220 ENSG00000162873
17  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910


Database:Transcription Target       Name:hsa_TTGTTT_V$FOXO4_01       ID:DB_ID:2416
C=2037; O=16; E=2.17; R=7.36; rawP=1.49e-10; adjP=1.25e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000125851 NA PCSK2 proprotein convertase subtilisin/kexin type 2 5126 ENSG00000125851
2  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
3  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
4  ENSG00000175161 NA CADM2 cell adhesion molecule 2 253559 ENSG00000175161
5  ENSG00000180772 NA AGTR2 angiotensin II receptor, type 2 186 ENSG00000180772
6  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069
7  ENSG00000197757 NA HOXC6 homeobox C6 3223 ENSG00000197757
8  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449
9  ENSG00000147255 NA IGSF1 immunoglobulin superfamily, member 1 3547 ENSG00000147255
10  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
11  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
12  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
13  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
14  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203
15  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
16  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361


Database:Transcription Target       Name:hsa_YNGTTNNNATT_UNKNOWN       ID:DB_ID:2392
C=361; O=8; E=0.39; R=20.78; rawP=4.41e-09; adjP=2.77e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
3  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
4  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069
5  ENSG00000180772 NA AGTR2 angiotensin II receptor, type 2 186 ENSG00000180772
6  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
7  ENSG00000197757 NA HOXC6 homeobox C6 3223 ENSG00000197757
8  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449


Database:Transcription Target       Name:hsa_CTGCAGY_UNKNOWN       ID:DB_ID:2137
C=756; O=9; E=0.81; R=11.16; rawP=9.20e-08; adjP=4.62e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
3  ENSG00000125355 NA FAM70A family with sequence similarity 70, member A 55026 ENSG00000125355
4  ENSG00000175161 NA CADM2 cell adhesion molecule 2 253559 ENSG00000175161
5  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
6  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
7  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
8  ENSG00000147255 NA IGSF1 immunoglobulin superfamily, member 1 3547 ENSG00000147255
9  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449


Database:Transcription Target       Name:hsa_V$EVI1_04       ID:DB_ID:1897
C=236; O=6; E=0.25; R=23.84; rawP=1.97e-07; adjP=7.60e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
3  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
4  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
5  ENSG00000197757 NA HOXC6 homeobox C6 3223 ENSG00000197757
6  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873


Database:Transcription Target       Name:hsa_V$HFH1_01       ID:DB_ID:1933
C=239; O=6; E=0.25; R=23.54; rawP=2.12e-07; adjP=7.60e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
2  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
3  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
4  ENSG00000197757 NA HOXC6 homeobox C6 3223 ENSG00000197757
5  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449
6  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873


Database:Transcription Target       Name:hsa_V$GATA_C       ID:DB_ID:1989
C=263; O=6; E=0.28; R=21.39; rawP=3.71e-07; adjP=1.03e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
3  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
4  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
5  ENSG00000197757 NA HOXC6 homeobox C6 3223 ENSG00000197757
6  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873


Database:Transcription Target       Name:hsa_V$HEB_Q6       ID:DB_ID:2209
C=263; O=6; E=0.28; R=21.39; rawP=3.71e-07; adjP=1.03e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000125355 NA FAM70A family with sequence similarity 70, member A 55026 ENSG00000125355
2  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
3  ENSG00000162873 NA KLHDC8A kelch domain containing 8A 55220 ENSG00000162873
4  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069
5  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
6  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873


Database:Transcription Target       Name:hsa_CTTTAAR_UNKNOWN       ID:DB_ID:2170
C=960; O=9; E=1.02; R=8.79; rawP=6.80e-07; adjP=1.71e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163029 NA SMC6 structural maintenance of chromosomes 6 79677 ENSG00000163029
2  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
3  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
4  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
5  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
6  ENSG00000187123 NA LYPD6 LY6/PLAUR domain containing 6 130574 ENSG00000187123
7  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
8  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
9  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).